ご連絡いただきましてありがとうございます。
管理画面よりキャッシュクリアはしております。
エラーログには下記のように表示されておりますが、ここから原因がわかりましたらご教示いただけますと幸いです。

[2018-08-11 19:33:08,437194] eccube.INFO [4b0d1cd6] [bcf8a664] [NULL] [LogListener:logResponse:96] - < 500 [GET, /rental.shop/entry, 121.211.112.57, https://www.pfizzjapan.com/rental.shop/entry, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:08,435661] eccube.CRITICAL [4b0d1cd6] [bcf8a664] [NULL] [LogListener:logException:112] - Twig_Error_Syntax: Unknown "is_object" function in "Form/form_layout.twig" at line 131. (uncaught exception) at /home/users/1/lolipop.jp-dp32214238/web/rental.shop/vendor/twig/twig/lib/Twig/ExpressionParser.php line 574 {"exception":"[object] (Twig_Error_Syntax(code: 0): Unknown \"is_object\" function in \"Form/form_layout.twig\" at line 131. at /home/users/1/lolipop.jp-dp32214238/web/rental.shop/vendor/twig/twig/lib/Twig/ExpressionParser.php:574)"} [GET, /rental.shop/entry, 121.211.112.57, https://www.pfizzjapan.com/rental.shop/entry, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:08,420518] eccube.CRITICAL [4b0d1cd6] [bcf8a664] [NULL] [LogListener:logException:112] - Twig_Error_Syntax: Unknown "is_object" function in "Form/form_layout.twig" at line 131. (uncaught exception) at /home/users/1/lolipop.jp-dp32214238/web/rental.shop/vendor/twig/twig/lib/Twig/ExpressionParser.php line 574 {"exception":"[object] (Twig_Error_Syntax(code: 0): Unknown \"is_object\" function in \"Form/form_layout.twig\" at line 131. at /home/users/1/lolipop.jp-dp32214238/web/rental.shop/vendor/twig/twig/lib/Twig/ExpressionParser.php:574)"} [GET, /rental.shop/entry, 121.211.112.57, https://www.pfizzjapan.com/rental.shop/entry, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:08,364900] eccube.INFO [4b0d1cd6] [bcf8a664] [NULL] [RouterListener:onKernelRequest:145] - Matched route "block_search_product". {"route_parameters":{"_controller":"\\Eccube\\Controller\\Block\\SearchProductController::index","_route":"block_search_product"},"request_uri":"https://www.pfizzjapan.com/rental.shop/block/search_product"} [GET, /rental.shop/entry, 121.211.112.57, https://www.pfizzjapan.com/rental.shop/entry, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:08,363251] eccube.INFO [4b0d1cd6] [bcf8a664] [NULL] [RouterListener:onKernelRequest:145] - Matched route "block_login". {"route_parameters":{"_controller":"\\Eccube\\Controller\\Block\\LoginController::index","_route":"block_login"},"request_uri":"https://www.pfizzjapan.com/rental.shop/block/login"} [GET, /rental.shop/entry, 121.211.112.57, https://www.pfizzjapan.com/rental.shop/entry, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:08,356681] eccube.INFO [4b0d1cd6] [bcf8a664] [NULL] [RouterListener:onKernelRequest:145] - Matched route "block_cart". {"route_parameters":{"_controller":"\\Eccube\\Controller\\Block\\CartController::index","_route":"block_cart"},"request_uri":"https://www.pfizzjapan.com/rental.shop/block/cart"} [GET, /rental.shop/entry, 121.211.112.57, https://www.pfizzjapan.com/rental.shop/entry, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:08,162805] eccube.INFO [4b0d1cd6] [bcf8a664] [NULL] [LogListener:logRequest:83] - > GET /rental.shop/entry [GET, /rental.shop/entry, 121.211.112.57, https://www.pfizzjapan.com/rental.shop/entry, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:08,161796] eccube.INFO [4b0d1cd6] [bcf8a664] [NULL] [AnonymousAuthenticationListener:handle:62] - Populated the TokenStorage with an anonymous Token. [GET, /rental.shop/entry, 121.211.112.57, https://www.pfizzjapan.com/rental.shop/entry, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:08,158847] eccube.INFO [NULL] [bcf8a664] [NULL] [RouterListener:onKernelRequest:145] - Matched route "entry". {"route_parameters":{"_controller":"\\Eccube\\Controller\\EntryController::index","_route":"entry"},"request_uri":"https://www.pfizzjapan.com/rental.shop/entry"} [GET, /rental.shop/entry, 121.211.112.57, https://www.pfizzjapan.com/rental.shop/entry, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:06,696345] eccube.INFO [4b0d1cd6] [ccc5c791] [NULL] [LogListener:logResponse:96] - < 500 [GET, /rental.shop/entry, 121.211.112.57, NULL, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:06,694905] eccube.CRITICAL [4b0d1cd6] [ccc5c791] [NULL] [LogListener:logException:112] - Twig_Error_Syntax: Unknown "is_object" function in "Form/form_layout.twig" at line 131. (uncaught exception) at /home/users/1/lolipop.jp-dp32214238/web/rental.shop/vendor/twig/twig/lib/Twig/ExpressionParser.php line 574 {"exception":"[object] (Twig_Error_Syntax(code: 0): Unknown \"is_object\" function in \"Form/form_layout.twig\" at line 131. at /home/users/1/lolipop.jp-dp32214238/web/rental.shop/vendor/twig/twig/lib/Twig/ExpressionParser.php:574)"} [GET, /rental.shop/entry, 121.211.112.57, NULL, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:06,678261] eccube.CRITICAL [4b0d1cd6] [ccc5c791] [NULL] [LogListener:logException:112] - Twig_Error_Syntax: Unknown "is_object" function in "Form/form_layout.twig" at line 131. (uncaught exception) at /home/users/1/lolipop.jp-dp32214238/web/rental.shop/vendor/twig/twig/lib/Twig/ExpressionParser.php line 574 {"exception":"[object] (Twig_Error_Syntax(code: 0): Unknown \"is_object\" function in \"Form/form_layout.twig\" at line 131. at /home/users/1/lolipop.jp-dp32214238/web/rental.shop/vendor/twig/twig/lib/Twig/ExpressionParser.php:574)"} [GET, /rental.shop/entry, 121.211.112.57, NULL, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:06,615553] eccube.INFO [4b0d1cd6] [ccc5c791] [NULL] [RouterListener:onKernelRequest:145] - Matched route "block_search_product". {"route_parameters":{"_controller":"\\Eccube\\Controller\\Block\\SearchProductController::index","_route":"block_search_product"},"request_uri":"https://www.pfizzjapan.com/rental.shop/block/search_product"} [GET, /rental.shop/entry, 121.211.112.57, NULL, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:06,613953] eccube.INFO [4b0d1cd6] [ccc5c791] [NULL] [RouterListener:onKernelRequest:145] - Matched route "block_login". {"route_parameters":{"_controller":"\\Eccube\\Controller\\Block\\LoginController::index","_route":"block_login"},"request_uri":"https://www.pfizzjapan.com/rental.shop/block/login"} [GET, /rental.shop/entry, 121.211.112.57, NULL, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:06,607723] eccube.INFO [4b0d1cd6] [ccc5c791] [NULL] [RouterListener:onKernelRequest:145] - Matched route "block_cart". {"route_parameters":{"_controller":"\\Eccube\\Controller\\Block\\CartController::index","_route":"block_cart"},"request_uri":"https://www.pfizzjapan.com/rental.shop/block/cart"} [GET, /rental.shop/entry, 121.211.112.57, NULL, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:06,375558] eccube.INFO [4b0d1cd6] [ccc5c791] [NULL] [LogListener:logRequest:83] - > GET /rental.shop/entry [GET, /rental.shop/entry, 121.211.112.57, NULL, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:06,374590] eccube.INFO [4b0d1cd6] [ccc5c791] [NULL] [AnonymousAuthenticationListener:handle:62] - Populated the TokenStorage with an anonymous Token. [GET, /rental.shop/entry, 121.211.112.57, NULL, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]
[2018-08-11 19:33:06,371750] eccube.INFO [NULL] [ccc5c791] [NULL] [RouterListener:onKernelRequest:145] - Matched route "entry". {"route_parameters":{"_controller":"\\Eccube\\Controller\\EntryController::index","_route":"entry"},"request_uri":"https://www.pfizzjapan.com/rental.shop/entry"} [GET, /rental.shop/entry, 121.211.112.57, NULL, Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/68.0.3440.106 Safari/537.36]